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保存前加一句 myImage2.SetResolution(300, 300) 你设置的bMape不是保存的主画布 所以无效，设置分辨率就是 SetResolution（X,Y）
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Declare Sub mouse_event Lib "user32" Alias "mouse_event" (ByVal dwFlags As Integer, ByVal dx As Integer, ByVal dy As Integer, ByVal cButtons As Integer, ByVal dwExtraInfo As Integer)
Dim postion1 As New Point
mouse_event(H1 Or H8000, postion1.X * 65535 / 1366, postion1.Y * 65535 / 768, 0, 0)
'按绝对位置移动鼠标
'在鼠标坐标系统中，屏幕在水平和垂直方向上均匀分割成65535×65535个单元，
'当前所用显示屏分辨率为1366*768
'所以要进行如上转换
mouse_event(H2, 0, 0, 0, 0) '鼠标左键按下
mouse_event(H4, 0, 0, 0, 0) '鼠标左键弹起
msdn上有 mouse_event 的详解，大致使用如上
您可以用下面给出这一小段代码检测当前屏幕分辨率，然后根据结果作出反应──例如，重新调整窗体大小以适应用程序户分辨率。
Public Function CheckRez(pixelWidth As Long, pixelHeight As Long) As Boolean
'
Dim lngTwipsX As Long
Dim lngTwipsY As Long
'
' convert pixels to twips
lngTwipsX = pixelWidth * 15
lngTwipsY = pixelHeight * 15
'
' check against current settings
If lngTwipsX Screen.Width Then
CheckRez = False
Else
If lngTwipsY Screen.Height Then
CheckRez = False
Else
CheckRez = True
End If
End If
'
End Function
Next, run the following code at the start of the program:
If CheckRez(640, 480) = False Then
MsgBox "Incorrect screen size!"
Else
MsgBox "Screen Resolution Matches!"
End If
这篇文章介绍了VB.NET设置屏幕分辨率、颜色位数、刷新率
实例代码，有需要的朋友可以参考一下
复制代码
代码如下:
Private
Declare
Function
GetDeviceCaps
Lib
"gdi32"
(ByVal
hdc
As
Long,
ByVal
nIndex
As
Long)
As
Long
Private
Declare
Function
ChangeDisplaySettings
Lib
"user32"
Alias
"ChangeDisplaySettingsA"
(lpDevMode
As
Any,
ByVal
dwflags
As
Long)
As
Long
Private
Const
CCDEVICENAME
As
Long
=
32
Private
Const
CCFORMNAME
As
Long
=
32
Private
Const
DM_BITSPERPEL
As
Long
=
H40000
Private
Const
DM_PELSWIDTH
As
Long
=
H80000
Private
Const
DM_PELSHEIGHT
As
Long
=
H100000
Private
Const
DM_DISPLAYFLAGS
As
Long
=
H200000
Private
Const
DM_DISPLAYFREQUENCY
=
H400000
Private
Const
CDS_FORCE
As
Long
=
H80000000
Private
Const
BITSPIXEL
As
Long
=
12
Private
Const
HORZRES
As
Long
=
8
Private
Const
VERTRES
As
Long
=
10
Private
Const
VREFRESH
=
116
Private
Type
DEVMODE
dmDeviceName
As
String
*
CCDEVICENAME
dmSpecVersion
As
Integer
dmDriverVersion
As
Integer
dmSize
As
Integer
dmDriverExtra
As
Integer
dmFields
As
Long
dmOrientation
As
Integer
dmPaperSize
As
Integer
dmPaperLength
As
Integer
dmPaperWidth
As
Integer
dmScale
As
Integer
dmCopies
As
Integer
dmDefaultSource
As
Integer
dmPrintQuality
As
Integer
dmColor
As
Integer
dmDuplex
As
Integer
dmYResolution
As
Integer
dmTTOption
As
Integer
dmCollate
As
Integer
dmFormName
As
String
*
CCFORMNAME
dmUnusedPadding
As
Integer
dmBitsPerPel
As
Integer
dmPelsWidth
As
Long
dmPelsHeight
As
Long
dmDisplayFlags
As
Long
dmDisplayFrequency
As
Long
End
Type
Private
Sub
cmdChangeDesktopMode_Click()
Dim
DM
As
DEVMODE
With
DM
.dmPelsWidth
=
CInt(txtNewWidth.Text)
.dmPelsHeight
=
CInt(txtNewHeight.Text)
.dmBitsPerPel
=
CInt(txtNewColor.Text)
.dmDisplayFrequency
=
CInt(txtNewFreq.Text)
.dmFields
=
DM_PELSWIDTH
Or
DM_PELSHEIGHT
Or
DM_BITSPERPEL
Or
DM_DISPLAYFREQUENCY
.dmSize
=
LenB(DM)
End
With
If
ChangeDisplaySettings(DM,
CDS_FORCE)
Then
MsgBox
"错误!不支持此模式！"
End
If
End
Sub
Private
Sub
Form_Load()
txtOldWidth.Text
=
GetDeviceCaps(Me.hdc,
HORZRES)
txtOldHeight.Text
=
GetDeviceCaps(Me.hdc,
VERTRES)
txtOldColor.Text
=
GetDeviceCaps(Me.hdc,
BITSPIXEL)
txtOldFreq.Text
=
GetDeviceCaps(Me.hdc,
VREFRESH)
End
Sub